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2025
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Tuna bioactive peptides lead the way to a new era of ocean health
In the booming global ocean economy, technological innovation has become the core engine driving the high-quality development of the marine food industry. With the explosive growth in consumer demand for functional foods the deep development of marine biological resources carries more expectations.
As a leading enterprise in Shandong, a major marine province, Lanrun Group has seized the opportunities of the times, taking tuna bioactive peptides as its core breakthrough point, and pioneered the construction of a full-industry chain innovation system of "marine resources + biotechnology + health application", becoming one of the leaders in the domestic marine bioactive peptide field. This strategy not only responds to the national "blue granary" strategy but also redefines the value boundaries of the marine food industry.
Technological Innovation Leads the Transformation of the Marine Food Industry
Reporters saw that in the laboratory of Lanrun Bio, a national high-tech enterprise, researchers are focusing on analyzing tuna bioactive peptides (tuna collagen peptides). This marine active substance, 90% of whose molecular weight is between 500-800 Daltons, is becoming a strategic fulcrum for leveraging the hundreds of billions of health market.
Peptides are functional fragments of proteins. Small molecular peptides with an average molecular weight of less than 1000 Daltons can be directly absorbed by the intestines and enter the bloodstream to exert their effects. Compared with traditional proteins, small molecular peptides have significant advantages such as high absorption rate and strong biological activity, showing great potential in enhancing immunity, anti-aging, bone health, beauty, and scavenging free radicals. Their targeted absorption characteristics perfectly match the needs of the precise nutrition era and have become the "golden ingredient" of functional foods. With the same intake of 10 grams of protein, the absorption and utilization rate of small molecular peptides is as high as 98% compared to traditional protein powder.
The rise of tuna bioactive peptides is no accident. Compared with terrestrial animals, marine collagen peptides have better biocompatibility. Tuna, as a top deep-sea predator, maintains a body temperature of around 35℃ year-round, similar to that of humans. Its collagen is rich in essential amino acids such as hydroxyproline, proline, arginine, and glycine, and its molecular activity is significantly higher than that of ordinary fish.
Deep-Sea Treasure: The Outstanding Advantages of Tuna Bioactive Peptides
With its excellent characteristics, tuna bioactive peptides stand out among many similar products, showing leading advantages in the industry from molecular structure to application areas.
Traditional collagen has a large molecular weight and is difficult for the human body to absorb efficiently. Tuna bioactive peptides, however, have made a major breakthrough with the help of cutting-edge, proprietary technology—"directed enzymatic hydrolysis-low-temperature controllable enzymatic hydrolysis technology "—under strict enzymatic hydrolysis processes, the peptide chains are precisely cleaved, and the molecular weight is precisely controlled within the ideal range of 500-800 Daltons. Peptide molecules in this range are small in size and stable in structure, able to easily penetrate the skin barrier and enter cells to exert their effects. The transdermal absorption rate is significantly improved compared to traditional collagen, laying a solid foundation for the efficient delivery of nutrients.
Tuna collagen peptides are rich in various amino acid components and organic selenium and trace elements such as calcium. Glycine, proline, and hydroxyproline are not only key amino acids that make up collagen but also play an important role in human metabolism, such as participating in cell repair and promoting connective tissue formation. At the same time, the peptides are also rich in precious trace elements such as organic selenium and calcium. antioxidant can scavenge free radicals in the body, enhance immunity, and prevent various diseases; calcium is crucial for bone health and helps maintain bone density and strength. This combination of diverse nutrients provides comprehensive nourishment for the human body.
The raw materials for producing tuna bioactive peptides are all sourced from pollution-free bluefin tuna and yellowfin tuna from the deep sea at depths of 100-400 meters. These areas are far from land pollution, and the tuna grow in a clean environment. These high-quality tuna as raw materials ensure the sustainable use of fishery resources. From the deep sea to the product, every link is traceable, ensuring that every serving of tuna bioactive peptides used by consumers comes from a pure, natural, and sustainable source.
Tuna bioactive peptides have excellent pH stability and can be widely added to carriers such as beverages, dairy products, cosmetics, and biomedicine, solving the technical problem of traditional collagen coagulating when encountering acid, and can meet the consumption needs of different age groups.
Data Speaks, Scientific Evidence Builds Competitive Barriers
In experiments conducted in cooperation with research institutions, subjects supplemented 6g of tuna bioactive peptides daily, and after 8 weeks, their skin hydration increased by 31.2%. Third-party test reports show:
Antioxidant capacity: The ABTS antioxidant IC50 value is 0.58mg/ml, which is 2-8 times that of bovine bone peptide.
Bone health: Tuna bone collagen is rich in peptide segments with a C-terminus of glutamic acid, glycine, and proline, which can effectively activate the MAPK/ERK signaling pathway, induce MC3T3-E1 cell differentiation, and upregulate RUNX2 at the gene and protein levels. It can provide a good microenvironment for the proliferation and differentiation of osteoblasts. Experiments have shown that the bone collagen peptide of Lanrun Bio can significantly increase osteoblast viability even at a very low concentration of 2μg/ml.
Amino acids: The total amount of amino acids reaches 92.3g/100g, an increase of 28% compared to traditional collagen.
Anserine: In 2024, the company's independently developed tuna anserine product reached an anserine content of 27.7% (tested by SGS).

As Academician Ding Dewen, director of the National Marine Innovation Laboratory, said: "Whoever masters the core technology of marine bioactive substances will control the future of the health industry." Shandong Lanrun Group Since its establishment, Shandong Lanrun Group has always focused on the meticulous cultivation of the marine food industry, continuously climbing to the high end of the industrial chain. Relying on the advantageous location of the Rongcheng National Offshore Fisheries Base, the group invested more than 300 million yuan to build a first-class ultra-low temperature (-60℃) tuna processing and storage base in China, with a 100,000-level clean workshop and a fully automated intelligent production line. Its annual tuna processing capacity is among the world's leading. The group has cooperated with a team of experts and professors from Beijing University of Chemical Technology for three years to develop tuna bioactive peptides. This product has achieved a breakthrough innovation in the field of collagen peptide, which not only has rewritten industry technical standards but also constructed an industrial closed loop of "marine resources-biological transformation-precise nutrition." As of now, Lanrun Group has invested more than 100 million yuan in research and development, applying for 24 patents, including 8 invention patents, providing a textbook example for the transformation and upgrading of the traditional marine food industry.
From the deck of the fishing boat to the microscope in the laboratory, from the production line in the workshop to the consumer's table, Shandong Lanrun Group's tuna bioactive peptide has achieved a significant leap in the marine industry. In the exhibition hall, the molecular structure of the tuna bioactive peptide shines brightly on the LED screen—this is not only the company's innovative achievement but also a mark of the time for China's marine biotechnology to go global. On the journey of building a strong maritime nation, it is writing a glorious chapter for Chinese enterprises with the giant pen of technological innovation. (Sun Yan, Wang Zuqi)
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